Estrogen Alters Oxytocin mRNA Levels in the Preoptic Area
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چکیده
منابع مشابه
Regulation of GABA transporter activity and mRNA expression by estrogen in rat preoptic area.
This study has examined whether estrogen regulates GABA transporter synthesis and activity in the female rat brain. In the first experiment in situ hybridization studies examined the effects of ovariectomy on cellular GABA transporter-1 (GAT-1) mRNA content. A 25% decrease in GAT-1 mRNA expression was detected within the medial preoptic area (MPOA) but not the parietal cortex, magnocellular pre...
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Estrogen action is mediated through several types of receptors (ERs), such as ERα, ERβ and putative membrane ERs. Oxytocin receptor (OTR) and ER expression levels in the rat uterus are regulated by estrogen; however, which types of ERs are involved has not been elucidated. This study examined OTR, ERα and ERβ levels in ovariectomized rats treated with 17β-estradiol (E2), an ERα agonist (PPT), a...
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Corresponding Author: Camila Infantosi Vannucchi Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo (USP), Rua Prof. Orlando Marques de Paiva, 87, São Paulo, 05508-270, Brazil Ph: +55 11 30911423 Email: [email protected] Abstract: Placenta is considered an important endocrine organ during gestation, as well as can also serve as a target or...
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Estradiol (E2) is important in activation of male reproductive behaviors, and masculinizes morphology of associated brain regions in a number of mammalian and avian species. In contrast, it is testosterone, rather than its metabolites, that is the most potent activator of male sexual behavior in green anole lizards. As in other vertebrate groups, however, E2 is critical for receptivity in femal...
متن کاملOxytocin in the medial preoptic area facilitates male sexual behavior in the rat.
Oxytocin (OT) is a versatile neuropeptide that is involved in a variety of mammalian behaviors, and its role in reproductive function and behavior has been well established. The majority of pharmacological studies of the effects of OT on male sexual behavior have focused on the paraventricular nucleus (PVN), ventral tegmental area (VTA), hippocampus, and amygdala. Less attention has been given ...
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ژورنال
عنوان ژورنال: Journal of Neuroendocrinology
سال: 1989
ISSN: 0953-8194,1365-2826
DOI: 10.1111/j.1365-2826.1989.tb00115.x